教授　森　裕二

トップページ　研究内容　論文　森裕二教授　坂井健男准教授　研究室のメンバー　写真　授業関係　リンクTop_Page.htmlResearch.htmlPublications.htmlTakeo_Sakai.htmlMembers.htmlPictures.htmlClasses.htmlLinks.htmlshapeimage_1_link_0shapeimage_1_link_1shapeimage_1_link_2shapeimage_1_link_3shapeimage_1_link_4shapeimage_1_link_5shapeimage_1_link_6shapeimage_1_link_7shapeimage_1_link_8
 

名前

森　裕二 (薬学博士)


連絡先

〒468-8503　名古屋市天白区八事山150

名城大学薬学部　分子設計化学研究室

TEL：052-839-2658

FAX：052-834-8090

E-mail：mori

(の後に@meijo-u.ac.jp)


略歴

1978年3月　 　　 京都大学大学院薬学研究科博士課程修了（薬学博士）

1978年4月　　 　 名城大学薬学部助手

1983～85年　　　米国コロンビア大学化学科博士研究員（W. C. Still 教授）

1991年4月　　　　名城大学講師（薬化学）

1993年4月　　　　名城大学助教授（薬化学）

2000年4月　　　　名城大学教授（分子設計化学）


受賞歴

1990年　　　　　　日本薬学会東海支部学術奨励賞

1993年　　　　　　日本薬学会奨励賞　

2018年　　　　　　日本薬学会賞 


資格

薬剤師免許


Publications (1995年以降の主なもの)

総説

  1. 1.Mori, Y. Development of New Synthetic Methods Using Oxiranyl Anions and Application in the Syntheses of Polycyclic Ether Marine Natural Products, Chem. Pharm. Bull. 2019, 67, 1–17.

  2. 2.Sakai, T.; Mori, Y. Strategies for Brevisamide Synthesis, Based on the Method for Constructing the Tetrahydropyranyl Core, Heterocycles, 2017, 95, 81–115

  3. 3.Mori, Y. Total Synthesis of Gambierol, Heterocycles, 2010, 81, 2203–2228.

  4. 4.Mori, Y.; Yaegashi, K. Stereocontrolled Synthesis of Marine Polycyclic Ethers by Oxiranyl Anion Strategy, Recent Research Developments in Organic Chemistry, 1999, 3, 207–217.

  5. 5.Mori, Y. Oxiranyl Anions as Nucleophilic Epoxides Reactions and Synthetic Applications Reviews on Heteroatom Chemistry. 1997, 17, 183–211.

  6. 6.森　裕二,  求核性エポキシドとしてのオキシラニルアニオンの発生と反応, 有機合成化学協会誌 1997, 55, 176–185.


原著論文

  1. 7.Sakai, T.; Mizuno, S.; Sone, A.; Hori, Y.; Yamazaki, W.; Takazawa, K.; Mori, Y. Biomimetic construction of a syn-2,7-dimethyloxepane ring via 7-endo cyclization. J. Org. Chem. accepted. DOI: 10.1021/acs.joc.1c02600.

  2. 8.Sakai, T.; Okumura, C.; Futamura, M.; Noda, N.; Nagae, A.; Kitamoto, C.; Kamiya, M.; Mori, Y. Gold(I)-Catalyzed Cyclization−3-Aza-Cope−Mannich Cascade and Its Application to the Synthesis of Cephalotaxine. Org. Lett. 2021, 23, 4391–4395.

  3. 9.Sakai, T.; Hata, K.; Kitamura, Y.; Ishibashi, R.; Mori, Y. Synthesis of the ABCD fragment of gymnocin-B. Tetrahedron Lett. 2019, 60, 151261.

  4. 10.Sakai, T.; Sakakibara, H.; Omoto, Y.; Tsunekawa, M.; Hadano, Y.; Kato, S.; Mori, Y. Synthesis of the GHIJKL Fragment of Gymnocin-B. Org. Lett. 2019, 21, 6864–6868.

  5. 11.Sakai, T.; Tatematsu, T.; Fukuta, A.; Kasai, S.; Hayashi, K.; Mori, Y. Benzyl Acetylcarbamate Potassium Salt (BENAC-K): A Simple Nucleophilic N-Acetamide Equivalent. Synthesis 2019, 51, 3638–3650.

  6. 12.Sakai, T.; Noda, N.; Fujimoto, C.; Ito, M.; Takeuchi, H.; Nishiwaki, M.; Mori, Y. Ion-Pair Extraction of Quaternary Ammoniums Using Tetracyanocyclopentadienides and Synthetic Application for Complex Ammoniums. Org. Lett. 2019, 21, 3081–3085.

  7. 13.Sakai, T.; Hattori, M.; Tada, A.; Matsuoka, J.; Mori, Y. Nucleophilic Addition to N-Benzoylisoquinolinium Cation Catalyzed by Sodium Tetracyanocyclopentadienides. Heterocycles 2019, 99, 703–715. (Professor Fukuyama’s memorial issue)

  8. 14.Sakai, T.; Aoyama, K.; Oshima, R.; Furukawa, K.; Mori, Y. Stereoinversion of a Tertiary Alcohol on a THP Ring: a Recovery Route to an Intermediate for Gymnocin-A. Heterocycles 2018, 97, 523–540. (Professor Tomioka’s memorial issue) Sakai, T.; Nagao, Y.; Nakamura, Y.; Mori, Y. Methanolysis of the Cyclic Acetal Function of NanoKid Catalyzed by NanoGoblin, the Pyridinium Salt of Tetracyanocyclopentadienide. ACS Omega 2017, 2, 8543–8549.

  9. 15.Sakai, T.; Ishihara, A.; Mori, Y. Synthesis of the KLMN fragment of gymnocin-A from the FGH fragment. J. Org. Chem. 2017, 82, 3976–3981.

  10. 16.Sakai, T.; Matsuoka, J.; Shintai, M.; Mori, Y. CAr-O Rotamers in 3,3′-disubstituted BINOL esters. J. Org. Chem. 2017, 82, 3276–3283.

  11. 17.Sakai, T.; Fukuta, A.; Nakamura, K.; Nakano, M.; Mori, Y. Total Synthesis of Brevisamide using an Oxiranyl Anion Strategy. J. Org. Chem. 2016, 81, 3799–3808.

  12. 18.Sakai, T.; Bito, M.; Itakura, M.; Sato, H.; Mori, Y. Acceleration of Acid-Catalyzed Hydrolysis in a Biphasic System by Sodium Tetracyanocyclopentadienides. Chem. Pharm. Bull. 2016, 64, 930–934.

  13. 19.Sakai, T.; Matsushita, S.; Arakawa, S.; Mori, K.; Tanimoto, M.; Tokumasu, A.; Yoshida, T.; Mori, Y. Total Synthesis of Gymnocin-A. J. Am. Chem. Soc. 2015, 137, 14513–14516.

  14. 20.Okutani, M.; Mori, Y. Synthesis of Alkynes from Vinyl Triflates Using Tetrabutylammonium Fluoride. Chem. Pharm. Bull. 2015, 63, 393–396.

  15. 21.Sakai, T.; Matsushita, S.; Arakawa, S.; Kawai, A.; Mori, Y. Synthetic study of gymnocin-A: synthesis of the ABC ring fragment. Tetrahedron Lett. 2014, 55, 6557–6560.

  16. 22.Sakai, T.; Asano, H.; Furukawa, K.; Oshima, R.; Mori, Y. Synthesis of the KLMN Fragment of Gymnocin-A Using Oxiranyl Anion Convergent Methodology. Org. Lett. 2014, 16, 2268–2271.

  17. 23.Sakai, T.; Seo, S.; Matsuoka, J.; Mori, Y. Synthesis of Functionalized Tetracyanocyclopentadienides from Tetracyanothiophene and Sulfones. J. Org. Chem. 2013, 78, 10978–10985.

  18. 24.Suzuki, Y.; Kuwabara, A.; Koizumi, Y.; Mori, Y. Synthesis of fused tetrahydropyrans by hydroalkoxylation of δ-hydroxy allenes. Tetrahedron 2013, 69, 9086–9095.

  19. 25.Sakai, T.; Sugimoto, A.; Tatematsu, H.; Mori, Y. Divergent Synthesis of trans-Fused Polycyclic Ethers by a Convergent Oxiranyl Anion Strategy. J. Org. Chem. 2012, 77, 11177–11191.

  20. 26.Sakai, T.; Ito, S.; Furuta, H.; Kawahara, Y.; Mori, Y. Mechanism of the Regio- and Diastereoselective Ring Expansion Reaction Using Trimethylsilyldiazomethane, Org. Lett. 2012, 14, 4564–4567.

  21. 27.Sakai, T.; Sugimoto, A.; Mori, Y. A Convergent Strategy for the Synthesis of Polycyclic Ethers by Using Oxiranyl Anions, Org. Lett. 2011, 13, 5850–5853.

  22. 28.Furuta, H.; Hasegawa, Y.; Hase, M.; Mori, Y. Total Synthesis of Gambierol by Using Oxiranyl Anions, Chem. Eur. J. 2010, 16, 7586–7595.

  23. 29.Furuta, H.; Hasegawa, Y.; Mori, Y. Total Synthesis of Gambierol, Org. Lett. 2009, 11, 4382–4385.

  24. 30.Okutani, M.; Mori, Y. Conversion of Bromoalkenes into Alkynes by Wet Tetra-n-butylammonium Fluoride. J. Org. Chem. 2009, 74, 442–444.

  25. 31.Mori, Y.; Futamura, Y.; Horisaki, K. Regioselective Aliphatic Retro-[1,4]-Brook Rearrangements, Angew. Chem. Int. Ed. 2008, 47, 1091–1093.

  26. 32.Okutani, M.; Mori, Y. Tetrabutylammonium fluoride-induced dehydrobromination of vinyl bromides to terminal acetylenes Tetrahedron Lett. 2007, 48, 6856–6859.

  27. 33.Matsugi, M.; Hasegawa, M.; Sadachika, D. Okamoto, S.; Tomioka, M.; Ikeya, Y.; Masuyama, A.; Mori, Y. Preparation and condensation reactions of a new light-fluorous Mukaiyama reagent: reliable purification with fluorous solid phase extraction for esters and amides, Tetrahedron Lett. 2007, 48, 4147–4150.

  28. 34.Hiramatsu, N.; Mori, Y. Synthesis of the 37-epi-HIJ ring system of adriatoxin, Heterocycles 2006, 69, 437–446.

  29. 35.Hiramatsu, N.; Mori, Y. A stereoselective route to multi-substituted tetrahydropyrans by vinyl radical cyclization Tetrahedron 2005, 61, 8589–8597.

  30. 36.Furuta, H.; Hase, M.; Noyori, R.; Mori, Y. Synthesis of the ABCD Ring of Gambierol, Org. Lett. 2005, 7, 4061–4064.

  31. 37.Mori, Y.; Takase, T.; Noyori, R. Iterative synthesis of the ABCDEF-ring system of yessotoxin and adriatoxin, Tetrahedron Lett. 2003, 44, 2319–2322.

  32. 38.Furuta, H.; Takase, T.; Hayashi, H.; Noyori, R.; Mori, Y. Synthesis of trans-fused polycyclic ethers with angular methyl groups using sulfonyl-stabilized oxiranyl anions, Tetrahedron 2003, 59, 9767–9777.

  33. 39.Mori, Y.; Nogami, K.; Hayashi, H.; Noyori, R. Sulfonyl-Stabilized Oxiranyllithium-Based Approach to Polycyclic Ethers. Convergent Synthesis of the ABCDEF-Ring System of Yessotoxin and Adriatoxin, J. Org. Chem. 2003, 68, 9050–9060.

  34. 40.Mori, Y.; Hayashi, H. Synthetic studies of yessotoxin, a polycyclic ether implicated in diarrhetic shell®sh poisoning: convergent synthesis of the BCDE ring system via an alkyne intermediate, Tetrahedron 2002, 58, 1789–1797.

  35. 41.Mori, Y.; Hayashi, H.; Practical Synthesis of 1,3-O-Di-tert-butylsilylene-Protected d- and l-Erythritols as a Four-Carbon Chiral Building Block, J. Org. Chem. 2001, 66, 8666–8668.

  36. 42.Mori, Y.; Mitsuoka, S.; Furukawa, H. A simple convergent synthesis of trans-fused six-membered polycyclic ethers, Tetrahedron Lett. 2000, 41, 4161–4164.

  37. 43.Mori, Y.; Yaegashi, K.; Furukawa, H. Synthesis of trans-fused tetrahydropyrans via intramolecular cyclization of a-bromo-g'-hydroxy ketones, Tetrahedron Lett. 1999, 40, 7239–7242.

  38. 44.Mori, Y.; Sawada, T.; Furukawa, H. Synthesis of (6S,7S,9R,10R)-6,9-Epoxynonadec-18-ene-7,10-diol, a Marine Epoxy Lipid Isolated from the Brown Alga, Notheia anomala, by an Oxiranyl Anion Strategy, Tetrahedron Lett. 1999, 40, 731–734.

  39. 45.Wu, T.-S.; Chan, Y.-Y.; Leu, Y.-L.; Wu, P.-L.; Li, C.-Y.; Mori, Y. Four Aristolochic Acid Esters of Rearranged ent-Elemane Sesquiterpenes from Aristolochia heterophylla, J. Nat. Prod. 1999, 62, 348–351.

  40. 46.Mori, Y.; Furuta, H.; Takase, T.; Mitsuoka, S.; Furukawa, H. Synthesis of methyl-substituted trans-fused tetrahydropyransvia 6-endo cyclization, Tetrahedron Lett. 1999, 40, 8019–8022.

  41. 47.Mori, Y.; Yaegashi, K.; Furukawa, H. Formal Total Synthesis of Hemibrevetoxin B by an Oxiranyl Anion Strategy, J. Org. Chem. 1998, 63, 6200–6209.

  42. 48.Mori, Y.; Yaegashi, K.; Furukawa, H. Stereoseleetive Synthesis of the 6,7,6- and 6,7,7-Ring Systems of Polycyclic Ethers by 6-endo Cyclization and Ring Expansion, Tetrahedron 1997, 53, 12917–12932.

  43. 49.Mori, Y.; Yaegashi, K.; Furukawa, H. Oxiranyl Anions in Organic Synthesis: Application to the Synthesis of Hemibrevetoxin B, J. Am. Chem. Soc. 1997, 119, 4557–4558.

  44. 50.Mori, Y. Reiterative Synthesis of trans-Fused Polytetrahydropyrans Using the Oxiranyl Anion, Chem. Eur. J. 1997, 3, 849–852.

  45. 51.Mori, Y.; Yaegashi, K.; Iwase, K.; Yamamori, Y.; Furukawa, H. Alkylation of Oxiranyl Anions, Tetrahedron Lett. 1996, 37, 2605–2608.

  46. 52.Mori, Y.; Yaegashi, K.; Furukawa, H. A New Strategy for the Reiterative Synthesis of trans-Fused Tetrahydropyrans via Alkylation of Oxiranyl Anion and 6-endo Cyclization, J. Am. Chem. Soc. 1996, 118, 8158–8159.

  47. 53.Mori, Y.; Sawada, T.; Sasaki, N.; Furukawa, H. A Simple Strategy for Determining the Absolute Configurations of Acyclic 1,2,4,6,8-Pentols, J. Am. Chem. Soc. 1996, 118, 1651–1656.

  48. 54.Mori, Y.; Asai, M.; Kawade, J.; Furukawa, H. Total Synthesis of the Polyene Macrolide Antibiotic Roxaticin. II. Total Synthesis of Roxaticin, Tetrahedron 1995, 51, 5315–5330.

  49. 55.Mori, Y.; Asai, M.; Okumura, A.; Furukawa, H. Total Synthesis of the Polyene Macrolide Antibiotic Roxaticin. I. Synthesis of the Polyol Fragment of Roxaticin Using a Four-Carbon Chain Extension Strategy, Tetrahedron 1995, 51, 5299–5314.

  50. 56.Mori, Y.; Furukawa, H. A Difference CD Method for Determining Absolute Stereochemistry of Acyclic 1,2,4-Triols, Tetrahedron 1995, 51, 6725–6738.