衛生化学研究室 ( HYGIENIC CHEMISTRY )
| 教授 | 神野 透人（Professor, Hideto Jinno, Ph.D.） |
|---|---|
| 助教 | 岡本 誉士典（Assistant Professor, Yoshinori Okamoto, Ph.D.） |
| 助教 | 青木 明（Assistant Professor, Akira Aoki, Ph.D.） |
| ① | 環境化学物質の環境動態・代謝と内分泌撹乱作用・変異原性発現およびその制御に関する研究 |
|---|---|
| ② | 食品衛生・環境汚染に関する研究 |
| ③ | 多能性幹細胞の衛生薬学研究への応用 |
| Yoshinori Okamoto, Koji Ueda, and Nakao Kojima: Potential risks of phthalate esters: Acquisition of endocrine-disrupting activity during environmental and metabolic processing.
J. Health Sci.，57, 497-503 (2011) |
| Yoshinori Okamoto, Chitose Toda, Koji Ueda, Kiyomatsu Hashizume, and Nakao Kojima：Transesterification in the microbial degradation of phthalate esters.
J. Health Sci.，57, 293-299 (2011) |
| Yoshihiko Nishino, Motozumi Ando, Rena Makino, Koji Ueda, Yoshinori Okamoto, and Nakao Kojima：Different mechanisms between copper and iron in catecholamines-mediated oxidative DNA damage and disruption of gene expression in vitro.
Neurotox. Res.，20, 84-92 (2011) |
| Motozumi Ando, Koji Ueda, Yoshinori Okamoto, and Nakao Kojima：Combined effects of manganese, iron, copper, and dopamine on oxidative DNA damage.
J. Health Sci.，57, 204–209 (2011) |
| Motozumi Ando, Hiroyuki Nishida, Koji Ueda, Kazuo Itoh, Yoshinori Okamoto, and Nakao Kojima：Preparation of oligoselenodiglutathiones and their suppressive effects on oxidative DNA damage induced by catechol and copper.
J. Health Sci.，57, 72–77 (2011) |
| Tsuyoshi Nakai, Motozumi Ando, Yoshinori Okamoto, Koji Ueda, and Nakao Kojima：Modulation of oxidative DNA damage and DNA-crosslink formation induced bycis-diammine-tetrachloro-platinum(IV) in the presence of endogenous reductants J. Inorg. Biochem.，105, 1–5 (2011) |
| Naomi Suzuki, Xiaoping Liu, Y. R. Santosh Laxmi, Kanako Okamoto, Hyo Jeong Kim, Guangxiang Zhang, John J. Chen, Yoshinori Okamoto, and Shinya Shibutani：Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen Int. J. Cancer.，128, 974–982 (2011) |
| Motozumi Ando, Hiroyuki Nishida, Yoshihiko Nishino, Manabu Ohbayashi, Koji Ueda, Yoshinori Okamoto, and Nakao Kojima：Carbonyl side-chain of catechol compounds is a key structure for the suppression of copper-associated oxidative DNA damage in vitro Toxicol. Lett.，199, 213–217 (2010) |
| Hiroyuki Nishida, Motozumi Ando, Kazuo Itoh, Koji Ueda, Yujiro Nishida, Yoshinori Okamoto, Chitose Toda, and Nakao Kojima：Production of polyselenodipenicillamines, unique selenium compounds Chem. Pharm. Bull., 58, 957–960 (2010) |
| 安藤基純、西田博之、伊藤和男、岡本誉士典、植田康次、小嶋仲夫：ペニシラミンセレノトリスルフィドはDNA鎖切断および酸化的DNA損傷を抑制する 名城大学総合研究所総合学術研究論文集, 9, 27–33 (2010) |
| Y. R. Santosh Laxmi, Xiaoping Liu, Naomi Suzuki, Sung Yeon Kim, Kanako Okamoto, Hyo Jeong Kim, Guangxiang Zhang, John J. Chen, Yoshinori Okamoto, and Shinya Shibutani：Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions Int. J. Cancer.，127, 1718–1726 (2010) |
| Yoshinori Okamoto, Xiaoping Liu, Naomi Suzuki, Kanako Okamoto, Hyo Jeong Kim, Y.R. Santosh Laxmi, Kazutoshi Sayama, and Shinya Shibutani：Equine estrogen-induced mammary tumors in rats Toxicol. Lett.，193, 224-228 (2010) |
| 戸田千登世、安藤基純、植田康次、橋爪清松、小嶋仲夫：たばこの主流煙および副流煙が示す酸化的DNA損傷作用 名城大学総合研究所総合学術研究論文集.，8, 47-52 (2009) |
| Motozumi Ando, Koji Ueda, Rena Makino, Yoshihiko Nishino, Hiroyuki Nishida, Chitose Toda, Yoshinori Okamoto, and Nakao Kojima：Involvement of DNA conformational change induced by rearrangement of copper-coordination geometry in oxidative DNA damages caused by copper and dopamine J. Health Sci.，55, 319–323 (2009) |
| 植田康次：化学物質の遺伝子及び遺伝子発現への影響 YAKUGAKU ZASSHI.，129, 1501-1506 (2009) |
| Yoshinori Okamoto, Tomohiro Hayashi, Shinpei Matsunami, Koji Ueda, and Nakao Kojima：Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage Chem. Res. Toxicol.，21, 1594–1599 (2008) |
| Rena Kusu, Ami Oishi, Kimi Kakizawa, Tomomi Kimura, Chitose Toda, Kiyomatsu Hashizume, Koji Ueda, and Nakao Kojima：Effects of phthalate ester derivatives including oxidized metabolites on coactivator recruiting by PPARα and PPARγ Toxicol. in Vitro.，22, 1534–1538 (2008) |
| Motozumi Ando, Koji Ueda, Rena Makino, Yuta Komatsu, Tsuyoshi Nakai, Yoshihiko Nishino, Hiroki Mizuno, Manabu Ohbayashi, and Nakao Kojima：Conformation change and oxidative damage of DNA induced by copper-catechol redox system J. Res. Inst. Meijo Univ.，7, 81–88 (2008) |
| 小嶋仲夫（編集幹事）：必携・衛生試験法 第1版
金原出版（平成23年3月1日） |
| 小嶋仲夫（分担編集）：最新公衆衛生学 第5版 廣川書店（平成22年8月20日） |
| 小嶋仲夫（分担編集）：新しい衛生薬学 第7版 廣川書店（平成22年2月20日） |