in preparation    Jan. '12

 著 者  ( 学士、修士、博士、研究員 を主体に )
 大塚昭信,砂田久一,山本金平,檀上和美,/中垣正幸,Jens Thuro Carstensen
主な研究課題 [JPN] [ENG]
 医薬品の溶解、放出に関する研究         
   医薬品の放出 - マトリックス製剤からの放出過程 -  MEMO
   医薬品の溶解 - 粒子と錠剤の溶解過程 -       
MEMO
   医薬品の溶解 - 表面積変化と溶解過程 -
       MEMO
   速崩壊性錠剤
 界面化学に関する研究
   水溶液中におけるグリチルリチンの物理化学的性質   MEMO
 相互作用に関する研究
   分散-凝集
   付着力
   固体分散体
 製剤、製剤過程に関する研究
   粉体、顆粒、賦形剤、添加剤......の物性
   造粒
   生薬の製剤化

     PAGE for COLLABORATION 

 to HOME of Yonezawa [JPN] [ ENG ]  /Fac.Pharm., Meijo Univ.


   .
        

 
                     LIST of COLLABORATION [ENG]

青木 義弘 石田 純男 石野 隆三 伊藤 公一 伊藤 竜也 伊庭 克英 鵜飼 泰夫 江口 浩司 大島 孝雄 大橋 綾子 小川 正知 尾澤 正敏
垣内 裕治 加藤 保富 神谷 賢司 川口  剛 川瀬 秀一 川地 美幸 木村 美保 栗本 高志 小西  興 後藤 健太 近藤 留美
佐々木 緑 篠原  格 柴田 大地 嶋田 光男 島田 泰拓 白倉 健史 陣出 裕次 杉野 友章 杉本  学 鈴木  忍 砂田 真由 瀬古 則貴
高橋由美子 田坂真粧美 巽  恒冶 鶴見 裕子 朝長 良子 豊田 るみ
中山アヤコ 成田 洋子
長谷川浩司 服部 亜紀 服部 直人 畢 雲 霞 古橋ひとみ
水野 真理 宮永 和美
山口 秀夫 山崎 敏正 山路ひろこ 山田 英理 山田 陽子 山田 誉春 山本 昭夫 山本 朱美 山本 智子
若松しおり 和田 明子 渡辺 淳子
中村康彦 平井 淑子 福居 篤子
辛 英 姫 仲 偉 星 李 暁 曼 王 暁燕





























                                        top
 青木義広              32 
32Yoshihiro Aoki,  Yoshiharu Yamada,  Kazumi Danjo,  Yorinobu Yonezawa,  Hisakazu Sunada,
  Flocculation Kinetics of the Monodisperse System. II.
  Computer Simulation of Flocculation with Compaction by the Two-Dimensional Geometrical Random Coalescence Model
  Chem. Pharm. Bull., 43 (7), 1197 -1203 (1995)


.
                                        top  MEMO
 石田純男             4445474857,62 
44Yorinobu YONEZAWA,  Sumio Ishida,  Hisakazu SUNADA:
  Release from or through a Wax Matrix System.
  I. Basic Release Properties of the Wax Matrix System
  Chem. Pharm. Bull., 49(11), 1448 - 1451 (2001)
45Yorinobu YONEZAWA,  Sumio Ishida,  Shinobu SUZUKI, Hisakazu SUNADA
  Release from or through a Wax Matrix System.
  II. Basic Properties of  Release from or through the Wax Matrix System
  Chem. Pharm. Bull., 50( 2),    220 -   224 (2002)
47Yorinobu YONEZAWA,  Sumio Ishida,  Shinobu SUZUKI, Hisakazu SUNADA
  Release from or through a Wax Matrix System.
  III. Basic Properties of  Release through the Wax Matrix System
  Chem. Pharm. Bull., 50( 6),    814 -   817 (2002)
48Yorinobu YONEZAWA,  Sumio Ishida,  Shinobu SUZUKI, Hisakazu SUNADA
  Release from or through a Wax Matrix System.
  IV. Generalized Expression of Release Process for Reservoir Device Tablet
  Chem. Pharm. Bull., 50( 9),  1219 - 1222 (2002
)
57Yorinobu YONEZAWA,  Sumio Ishida, Hisakazu SUNADA:
  Release from or through a Wax Matrix System.
  V. Applicability of Square-Root Time Law Equation for Release from a Wax Matrix Tablet
  Chem. Pharm. Bull., 51( 8), 904 -908 (2003)

62Yorinobu Yonezawa,  Sumio Ishida, Hisakazu Sunada:
  Release from or through a Wax Matrix System.
  VI. Analysis and Prediction of the Entire Release Process of the Wax Matrix Tablet
  Chem. Pharm. Bull., 53( 8), 915 -918 (2005)


                                        top
 石野隆三             2528, 
25.山口秀夫,米澤頼信,檀上和美,砂田久一,瀬古則貴,石野隆三
  センナ末の造粒における粉体物性と顆粒物性の関係
  Hideo Yamaguchi, yorinobu yonezawa, Kazumi Danjo, Hisakazu Sunada, Noritaka Seko, Ryuzo Ishino:
  Relationship between Characteristics of Powder and Granule on Granulation of Senna Powder
  薬剤学,YAKUZAIGAKU, 53(1), 70-79 (1993)
28Yasutomi Kato, Hisakazu Sunada, Yorinobu Yonezawa, Ryuzo Ishino,
  Sustained Release Mechanisms of Wax Matrix System for Controlled Release
  Chem. Pharm. Bull., 42 (8), 1646 - 1650 (1994)


                                        top 
 伊藤公一
             (acknowledgement in 26), 

26Noritaka Seko, Hisakazu Sunada, Kazumi Danjo, Akinobu Otsuka, Yorinobu Yonezawa, Noboru Matsui,
 Pharmaceutical Preparation of Crude Drug Powder. III.
 The Effect of the Physical Properties of the Binder Solution on the Characteristics of the Granule from the Mixed Powders    
  Chem. Pharm. Bull., 41 (5), 937 - 941 (1993)

                                        top
 伊藤竜也              40
40.島田 泰拓,伊藤 竜也,米澤 頼信,砂田 久一,横須賀正彦,武林  敬
  カプセル表面に付着した汚染粉体の付着力とその除去
  Yasuhiro Shimada, Tatsuya Ito, Yorinobu Yonezawa, Hisakazu Sunada, Masahiko Yokosuka, Kei Takebayashi:
  Measurements of the Adhesive Force of Contaminative Particles on the Capsule Surface and Method of Their Removal   
  薬剤学,YAKUZAIGAKU, 60(1), 35-42 (2000)


.
                                        top   MEMO
 伊庭克英                2 
2.大塚昭信,米澤頼信,伊庭克英,巽 恒治,砂田久一,    
  水溶液中におけるグリチルリチンの物理化学的性質(第1報) 
  界面活性作用と会合体形成
  Akinobu Otsuka, Yorinobu Yonezawa, Katsuhide Iba, Tsuneji Tatsumi, Hisakazu Sunada:
  Physico-Chemical Properties of Glycyrrhizic Acid in Aqueous Media.I.
  I. Surface-active Properties and Formation of Melecular Aggregates
  薬学雑誌,YAKUGAKU ZASSHI, 96 (2), 203 - 208 (1976)


                                        top
 鵜飼泰夫      64
64.鵜飼泰夫,島田泰拓,米澤頼信,砂田久一:
  粉末セルロースの医薬品賦形剤としての評価 - 転動流動造粒法により製した顆粒及び錠剤について
  医薬品研究36(10),437-446(2005)

                                        top
 江口浩司              31 
31Haruo Sekizaki, Kazumi Danjo, Hiroshi Eguchi, Yorinobu Yonezawa, Hisakazu Sunada, Akinobu Otsuka,
  Solid-State Interaction of Ibuprofen with Polyvinylpyrrolidone
  Chem. Pharm. Bull., 43 (6), 988 - 993 (1995)


                                        top
 小川昌知 

                                        top
 大島孝雄              4954 
49.木村 美保,島田 泰拓,大島 孝雄,柴田 大地,服部 直人,米澤 頼信,砂田 久一,
  粉末セルロースの医薬品賦形剤としての評価
  Miho Kimura, Yasuhiro Shimada, Takao Oshima, Daichi Shibata, Naoto Hattori, Yorinobu Yonezawa, Hisakazu Sunada:
  The Evaluation of Powdered Cellulose as a Pharmaceutical Excipient
  薬剤学,YAKUZAIGAKU, 62(3),113-123 (2002)
54大島 孝雄,畢 雲霞,米澤 頼信,砂田 久一:
  
難溶性薬物を含有する湿式法による口腔内速崩壊錠 - 調製と崩壊機構の解明

  Takao Oshima, Yunxia Bi, Yorinobu Yonezawa, and Hisakazu Sunada
  Wet-CompressedRapodly Disintegrating Tablets in the Oral Cavity Containing High-Content Poorly Water-Soluble Model Drug
  - Preparation and Cralification of Disintegration Mechanism

  薬剤学,YAKUZAIGAKU, 63(1), 1 -11 (2003)


                                        top
 大橋あやこ
              (acknowledgement in 5). 63.
5. 山本金平、砂田久一、米澤頼信、大塚昭信、
  2-ヒドロキシアゾメチン誘導体のアルミニウムキレートのけい光強度に対するFree-Wilsonの解析法の適用
  分析化学 BUNSEKI KAGAKU, 28(3), 205-208 (1979)

  Kimpei Yamamoto, Hisakazu Sunada, Yorinobu Yonezawa, Akinobu Otsuka:
  Application of Free-Wilsons's Analitycal Method to the Fluorescence Intensities of Aluminum Chelate of 2-hydroxyazomethine Derivatives
  分析化学,BUNSEKI KAGAKU, 28, 205-208 (1979)

63中山アヤコ ,愛知史子,近藤東臣,砂田久一,米澤頼信,島田泰拓:
   中小病院における院内製剤の品質評価 - プロゲステロン膣坐剤 -
   医療薬学,31(10),802-807 (2005)

                                        top
 尾澤正敏              46  
46Masatoshi Ozawa, Koji Hasegawa, Yorinobu Yonezawa, Hisakazu Sunada:
  Preparation of Solid Dispersion for Ethenzamide-Carbopol and Theophyline-Carbopol System Using a Twin Screw Extruder    
  
Chem. Pharm. Bull., 50( 6),   802  -  807 (2002)


                                        top
 垣内裕治              (acknowledgement in 25). 
25.山口秀夫,米澤頼信,檀上和美,砂田久一,瀬古則貴,石野隆三,
  センナ末の造粒における粉体物性と顆粒物性の関係
  Hideo Yamaguchi, Yorinobu Yonezaw, Kazumi Danjo, Hisakazu Sunada, Noritaka Seko, Ryuzo Ishino
  Relationship between Characteristics of Powder and Granule on Granulation of Senna Powder
  薬剤学,YAKUZAIGAKU, 53(1), 70-79 (1993)

                                        top
 加藤保              28.   
28Yasutomi Kato, Hisakazu Sunada, Yorinobu Yonezawa, Ryuzo Ishino,
  Sustained Release Mechanisms of Wax Matrix System for Controlled Release
  Chem. Pharm. Bull., 42 (8), 1646 - 1650 (1994)


                                        top
 神谷賢司              (acknowledgement in 21). 
21Yorinobu Yonezawa, Kenji Shirakuara, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution of Solid Dosage Form. II.
  II. Equations for the Dissolution of Nondisintegrating Tablet under the Sink Condition
  Chem. Pharm. Bull., 39 (3), 769 - 772 (1991)

                                        top
 川口 剛              42.  
42Takeshi  Kawaguchi, Hisakazu Sunada, Yorinobu Yonezawa, Kazumi Danjo, Masaki Hasegawa,
  Tadashi Makino, Hiroshi Sakamoto, Kanji Fujita, Tadatugu Tanino, Hiroyasu Kokubo:
  Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator
  Pharmaceutical Development and Technology, 5 (2), 141- 151 (2000)


.
                                        top  MEMO
 川瀬秀一             293334 
29Yorinobu Yonezawa, Shuichi Kawase, Midori Sasaki, Itaru Shinohara, Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  V. New Form Equations for the Non-sink Dissolution of a Monodisperse System
  Chem. Pharm. Bull., 43 (2), 304 -310 (1995)
33Yorinobu Yonezawa,  Shuichi Kawase,  Midori Sasaki,  Akiko Wada,  Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  VI. Dissolution of Nondisintegrating Single Component Tablet under Non-Sink Condition
  Chem. Pharm. Bull., 43 (11), 1961 -1965 (1995)
34Yorinobu Yonezawa,  Shuichi Kawase,  Yuji Jinde,  Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  VII. Effect of Shape on the Dissolution of Nondisintegrating Single Component Tablet under Non-sink Condition
  Chem. Pharm. Bull., 44 (5), 1043 -1048 (1996)


                                        top
 川地美幸              (acknowledgement in 22). 
22. 山本金平、砂田久一、米澤頼信、大塚昭信、
  2-ヒドロキシフェニルアゾメチン及び2,2'-ジヒドロキシアゾベンゼン誘導体のガリウム及びアルミニウムキレートの物理化学的性質と蛍光強度との関係
  分析化学 BUNSEKI KAGAKU, 40, 495-498 (1991)

  Kimpei Yamamoto, Hisakazu Sunada, Yorinobu Yonezawa, Akinobu Otsuka:
  Relationship between the fluorescence intensities and physico-chemical properties of gallium and
  alminiumchelates of 2-hydroxyphenylazomethine and 2,2'-dihydroxyazobenzen derivatives

  分析化学,BUNSEKI KAGAKU, 40(9), 495-498 (1991)

                                        top
 木村美保              49. 
49木村 美保,島田 泰拓,大島 孝雄,柴田 大地,服部 直人,米澤 頼信,砂田 久一,
  粉末セルロースの医薬品賦形剤としての評価
  Miho Kimura, Yasuhiro Shimada, Takao Oshima, Daichi Shibata, Naoto Hattori, Yorinobu Yonezawa, Hisakazu Sunada:
  The Evaluation of Powdered Cellulose as a Pharmaceutical Excipient
  薬剤学,YAKUZAIGAKU, 62(3),113-123 (2002)

                                        top
 栗本高志              18. 
18Hisakazu Sunada, Yumiko Takahashi, Takashi Kurimoto, Yoshiko Hirai, Yorinobu Yonezawa, Akinobu Otsuka, Yoshiaki Kawashima,
  Flocculation Studies of Granulated Stearyl Alcohol on the Surface of Aqueous Media.    
  III. Changes of Aggromerate Structure in a Two-Dimensional System with Anionic Surface-Active Agent    
     
Chem. Pharm. Bull., 37 (12), 3355 - 3358 (1989)


                                        top
 小西 興      65
65.小西 興,砂田久一,米澤頼信,檀上和美:
  生薬粉末の製剤化 ? ローラーコンパクターを用いた乾式造粒法について
  Pharmaceutical Manufacturing of Crude Drug Powder - Dry Compacting Method with a Roller Compactor -
  薬剤学,66(2),151-159(2006)

                                        top
 後藤健太              38 
38Kenta Goto,  Hisakazu Sunada,  Kazumi Danjo,  Yorinobu Yonezawa,
  Pharmaceutical Evaluation of Multipurpose Excipients for Direct Compressed Tablet
  Manufacture: Comparison of the Capabilities of Multipurpose Excipients with Those in General Use
     
Drug Development and Industrial Pharmacy, 25(8), 869-878 (1999)


                                        top
 近藤留美 

.
                                        top  MEMO
 佐々木緑             272933
27Yorinobu Yonezawa, Itaru Shinohara, Midori Sasaki, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  IV. Equations for the Non-sink Dissolution of a Monodisperse System
  Chem. Pharm. Bull., 42 (2), 349 - 353 (1994)
29Yorinobu Yonezawa, Shuichi Kawase, Midori Sasaki, Itaru Shinohara, Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  V. New Form Equations for the Non-sink Dissolution of a Monodisperse System
  Chem. Pharm. Bull., 43 (2), 304 -310 (1995)
33Yorinobu Yonezawa,  Shuichi Kawase,  Midori Sasaki,  Akiko Wada,  Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  VI. Dissolution of Nondisintegrating Single Component Tablet under Non-Sink Condition
  Chem. Pharm. Bull., 43 (11), 1961 -1965 (1995)


.
                                        top  
 篠原 格             15161719202729  
Changes of Surface Area in the Dissolution of Crystalline Substances      MEMO
15Hisakazu Sunada, Itaru Shinohara, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  II. Dissolution and Simulation Curves for Mixed Systems of Sieved Particles
  Chem. Pharm. Bull., 37 (2), 467 - 470 (1989)
16Hisakazu Sunada, Itaru Shinohara, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
   IIII. Dissolution and Simulation curves for Symmetrical Particle-Size Distributed Model System
  Chem. Pharm. Bull., 37 (5), 1362 - 1365 (1989)
17Hisakazu Sunada, Itaru Shinohara, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  IV. Dissolution and Simulation Curves Estimated from Changes of Surface Area and Cube Root Law
  Chem. Pharm. Bull., 37 (7), 1889 - 1894 (1989)
19Yorinobu Yonezawa, Itaru Shinohara, Akinobu Otsuka, Hisakazu Sunada,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  V. Dissolution and Simulation Curves for Log-Normal Particle-Size-Distributed Model Systems
  Chem. Pharm. Bull., 38 (4), 1024 - 1026 (1990)
Dissolution of Solid Dosage Form                MEMO
20
Yorinobu Yonezawa, Itaru Shinohara, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution and Simulation Curves for Log-Normal Particle-Size-Distributed Model System
  Chem. Pharm. Bull., 38 (11), 3107 - 3111 (1990)
27Yorinobu Yonezawa, Itaru Shinohara, Midori Sasaki, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  IV. Equations for the Non-sink Dissolution of a Monodisperse System
  Chem. Pharm. Bull., 42 (2), 349 - 353 (1994)
29Yorinobu Yonezawa, Shuichi Kawase, Midori Sasaki, Itaru Shinohara, Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  V. New Form Equations for the Non-sink Dissolution of a Monodisperse System
  Chem. Pharm. Bull., 43 (2), 304 -310 (1995)


                                        top
 柴田大地               49,51,53 
49.木村 美保,島田 泰拓,大島 孝雄,柴田 大地,服部 直人,米澤 頼信,砂田 久一,
  粉末セルロースの医薬品賦形剤としての評価
  Miho Kimura, Yasuhiro Shimada, Takao Oshima, Daichi Shibata, Naoto Hattori, Yorinobu Yonezawa, Hisakazu Sunada:
  The Evaluation of Powdered Cellulose as a Pharmaceutical Excipient
  薬剤学,YAKUZAIGAKU, 62(3),113-123 (2002)

51柴田 大地,島田 泰拓,米澤 頼信,砂田 久一,大友  直也,笠原 健史、
  医薬分野におけるショ糖脂肪酸エステルの滑沢剤としての適用とその評価
  薬剤学,YAKUZAIGAKU, 62(4), 133 -145 (2002)
  Daichi Shibata, Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada, Naoya Otomo, Kenji Kasahara:
  Application and Evaluation of Sucrose Fatty Acid Esters as Lubricant in the Production of Pharmaceuticals
  薬剤学,YAKUZAIGAKU, 62(4), 133 -145 (2002)

53柴田 大地,島田 泰拓,米澤 頼信,砂田 久一,大友  直也,笠原 健史、
  医薬分野におけるショ糖脂肪酸エステルの滑沢剤としての適用とその評価
  Daichi Shibata, Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada, Naoya Otomo, Kenji Kasahara:
  Application and Evaluation of Sucrose Fatty Acid Esters as Lubricant in the Production of Pharmaceuticals
  医薬品研究、34(1)、9 - 19 (2003)

                                        top
 嶋田光男 

,
                                        top 
 島田泰拓             4041434951,52,56 
40島田 泰拓,伊藤 竜也,米澤 頼信,砂田 久一,横須賀正彦,武林  敬,
  カプセル表面に付着した汚染粉体の付着力とその除去
  Yasuhiro Shimada, Tatsuya Ito, Yorinobu Yonezawa, Hisakazu Sunada, Masahiko Yokosuka, Kei Takebayashi:
  Measurements of the Adhesive Force of Contaminative Particles on the Capsule Surface and Method of Their Removal 
  薬剤学,YAKUZAIGAKU, 60(1), 35-42 (2000)
41Yasuhiro Shimada,  Mayu Sunada,  Mari Mizuno,  Yorinobu Yonezawa,  Hisakazu Sunada,
  Kei Takebayashi,  Masahiko Yokosuka,  Haruki  Kimura:
  Measurement of the adhesive force of fine particles on tablet surface and method of their removal  
  
Drug Development and Industrial Pharmacy, 26(2), 149-158 (2000)

43島田 泰拓,米澤 頼信,砂田 久一,野中 隆盛,加藤 賢三,森下 広:
  微粒子間の付着力測定装置の開発
  Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada, Ryusei Nonaka, Kenzou Kato, Hiroshi Morishita:
  The Developement of an Apparatus for Measuring the Adhesive Force betwen Fine Particles
  粉体工学会誌,J. Soc. Powder Technol., Japan,  37(9), 658-664 (2000)
49.木村 美保,島田 泰拓,大島 孝雄,柴田 大地,服部 直人,米澤 頼信,砂田 久一,
  粉末セルロースの医薬品賦形剤としての評価
  Miho Kimura, Yasuhiro Shimada, Takao Oshima, Daichi Shibata, Naoto Hattori, Yorinobu Yonezawa, Hisakazu Sunada:
  The Evaluation of Powdered Cellulose as a Pharmaceutical Excipient
  薬剤学,YAKUZAIGAKU, 62(3),113-123 (2002
)
51.柴田 大地,島田 泰拓,米澤 頼信,砂田 久一,大友  直也,笠原 健史、
  医薬分野におけるショ糖脂肪酸エステルの滑沢剤としての適用とその評価
  薬剤学,YAKUZAIGAKU, 62(4), 133 -145 (2002)

  Daichi Shibata, Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada, Naoya Otomo, Kenji Kasahara:
  Application and Evaluation of Sucrose Fatty Acid Esters as Lubricant in the Production of Pharmaceuticals
  薬剤学,YAKUZAIGAKU, 62(4), 133 -145 (2002)

52Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada,
  Measurement and Evaluation of the Adhesive Force between Particles by the Direct Separation Method
  J. Pharm. Sci., 92( 3), 526-534 (2003)

56島田 泰拓,米澤 頼信,砂田 久一
  表面改質法を用いた微小粒子間付着力の制御とその評価
  粉体工学会誌、J. Soc. Powder Technol., Japan,  40(5), 334-338 (2003)

.
                                        top   MEMO
 白倉健史             2123. 
21Yorinobu Yonezawa, Kenji Shirakuara, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution of Solid Dosage Form.
  II. Equations for the Dissolution of Nondisintegrating Tablet under the Sink Condition
  Chem. Pharm. Bull., 39 (3), 769 - 772 (1991)
23Yorinobu Yonezawa, Kenji Shirakuara, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution of Solid Dosage Form.
  III. Equations for the Dissolution of a Nondisintegrating Single Component Tablet under a Nonsink Condition  
  Chem. Pharm. Bull., 39 (12), 3355 - 3358 (1991)


.
                                        top   MEMO
 陣出裕次              34  
34Yorinobu Yonezawa,  Shuichi Kawase,  Yuji Jinde,  Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  VII. Effect of Shape on the Dissolution of Nondisintegrating Single Component Tablet under Non-sink Condition   
  Chem. Pharm. Bull., 44 (5), 1043 -1048 (1996)


                                        top
 杉本 学              12 
12.砂田久一,杉本 学,米澤頼信,大塚昭信,
  インドプロフェン類化合物の生理活性と物理化学的性質との関係
  Hisakazu Sunada, Manabu Sugimoto, Yorinobu Yonezawa, Akinobu Otsuka:
  Relationship between Bioactivity and Physico-Chemical Properties of Indoprofen and Its Related Compounds   
  薬剤学,YAKUZAIGAKU, 48(1), 58-63 (1988)

                                        top
 杉野友章              (acknowledgement in 26). 
26Noritaka Seko, Hisakazu Sunada, Kazumi Danjo, Akinobu Otsuka, Yorinobu Yonezawa, Noboru Matsui,
  Pharmaceutical Preparation of Crude Drug Powder.
  III. The Effect of the Physical Properties of the Binder Solution on the Characteristics of the Granule from the Mixed Powders    
  Chem. Pharm. Bull., 41 (5), 937 - 941 (1993)

.
                                        top   MEMO
 鈴木 忍             454748
45Yorinobu Yonezawa,  Sumio Ishida,  Shinobu Suzuki, Hisakazu Sunada:
  Release from or through a Wax Matrix System.
  II. Basic Properties of  Release from or through the Wax Matrix System
  Chem. Pharm. Bull., 50( 2),    220 -   224 (2002)
47Yorinobu Yonezawa,  Sumio Ishida,  Shinobu Suzuki, Hisakazu Sunada:
  Release from or through a Wax Matrix System.
  III. Basic Properties of  Release through the Wax Matrix System
  Chem. Pharm. Bull., 50( 6),    814 -   817 (2002)
48Yorinobu Yonazawa,  Sumio Ishida,  Shinobu Suzuki, Hisakazu Sunada:
  Release from or through a Wax Matrix System.
  IV. Generalized Expression of Release Process for Reservoir Device Tablet
  Chem. Pharm. Bull., 50( 9), 1219 -1222 (2002)


                                        top
 砂田真由              41.  
41Yasuhiro Shimada,  Mayu Sunada,  Mari Mizuno,  Yorinobu Yonezawa,  Hisakazu Sunada,
  Kei Takebayashi,  Masahiko Yokosuka,  Haruki  Kimura:
  Measurement of the adhesive force of fine particles on tablet surface and method of their removal  
  Drug Development and Industrial Pharmacy, 26(2), 149-158 (2000)


                                        top
 瀬古則貴             2526 
25.山口秀夫,米澤頼信,檀上和美,砂田久一,瀬古則貴,石野隆三,
  センナ末の造粒における粉体物性と顆粒物性の関係
  Hideo Yamaguchi, Yorinobu Yonezaw, Kazumi Danjo, Hisakazu Sunada, Noritaka Seko, Ryuzo Ishino
  Relationship between Characteristics of Powder and Granule on Granulation of Senna Powder
  薬剤学,YAKUZAIGAKU, 53(1), 70-79 (1993)
26Noritaka Seko, Hisakazu Sunada, Kazumi Danjo, Akinobu Otsuka, Yorinobu Yonezawa, Noboru Matsui,
  Pharmaceutical Preparation of Crude Drug Powder. III.
  The Effect of the Physical Properties of the Binder Solution on the Characteristics of the Granule from the Mixed Powders    
  Chem. Pharm. Bull., 41 (5), 937 - 941 (1993)


                                        top
 高橋由美子       18.  
18Hisakazu Sunada, Yumiko Takahashi, Takashi Kurimoto, Yoshiko Hirai, Yorinobu Yonezawa,  Akinobu Otsuka, Yoshiaki Kawashima,
  Flocculation Studies of Granulated Stearyl Alcohol on the Surface of Aqueous Media.    
  III. Changes of Aggromerate Structure in a Two-Dimensional System with Anionic Surface-Active Agent    
  
Chem. Pharm. Bull., 37 (12), 3355 - 3358 (1989)


                                        top
 田坂真粧美       36 
36田坂真粧美,砂田 久一,米澤 頼信,
  高濃度の主薬を含有するコーティング用核粒子の調製と評価
  Masami Tasaka, Hisakazu Sunada, Yorinobu Yonezawa:
  Characterization of Core Particles for Film Cating with High Active Ingredient Content
  薬剤学,YAKUZAIGAKU, 59(2), 57-66(1999)


.
                                        top   MEMO
 巽 恒治                2 
2.大塚昭信,米澤頼信,伊庭克英,巽 恒治,砂田久一,    
  水溶液中におけるグリチルリチンの物理化学的性質(第1報) 
  界面活性作用と会合体形成
  Akinobu Otsuka, Yorinobu Yonezawa, Katsuhide Iba, Tsuneji Tatsumi, Hisakazu Sunada:
  Physico-Chemical Properties of Glycyrrhizic Acid in Aqueous Media.I.
  I. Surface-active Properties and Formation of Melecular Aggregates
  薬学雑誌,YAKUGAKU ZASSHI, 96 (2), 203 - 208 (1976)


                                        top
 鶴見裕子              (acknowledgement in 8). 
8. 米澤頼信、砂田久一、大塚昭信、中垣正幸
  水溶液中におけるグリチルリチンの物理化学的性質(第5報)
  グリチルリチンとコール酸ナトリウムとの混合溶液の臨界ミセル濃度
  薬学雑誌 YAKUGAKU ZASSHI, 103(10), 1085 - 1090 (1983)

  Yorinobu Yonezawa, Hisakazu Sunada, Akinobu Otsuka, Masayuki Nakagaku:
  Physico-Chemical Properties of Glycyrrhizic Acid in Aqueous Media.V.
  V. Critical Micelle Concentration of Mixed Solution of Glycyrrhizin and Sodium Cholate
  薬学雑誌,YAKUGAKU ZASSHI, 103 (10), 1085 - 1090 (1983)

                                        top
 朝長良子              (acknowledgement in 22). 
22. 山本金平、砂田久一、米澤頼信、大塚昭信、
  2-ヒドロキシフェニルアゾメチン及び2,2'-ジヒドロキシアゾベンゼン誘導体のガリウム及びアルミニウムキレートの物理化学的性質と蛍光強度との関係
  分析化学 BUNSEKI KAGAKU, 40, 495-498 (1991)

  Kimpei Yamamoto, Hisakazu Sunada, Yorinobu Yonezawa, Akinobu Otsuka:
  Relationship between the fluorescence intensities and physico-chemical properties of gallium and
  alminiumchelates of 2-hydroxyphenylazomethine and 2,2'-dihydroxyazobenzen derivatives

  分析化学,BUNSEKI KAGAKU, 40(9), 495-498 (1991)

                                        top
 豊田るみ              (acknowledgement in 13)
13Hisakazu Sunada, Akio Yamamoto, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  Chem. Pharm. Bull., 36 (7), 2557 - 2561 (1988)

 
中山アヤコ      63
63中山アヤコ ,愛知史子,近藤東臣,砂田久一,米澤頼信,島田泰拓:
   中小病院における院内製剤の品質評価 - プロゲステロン膣坐剤 -
   医療薬学31(10),802-807 (2005)

                                        top
 成田洋子              (acknowledgement in 22). 
22. 山本金平、砂田久一、米澤頼信、大塚昭信、
  2-ヒドロキシフェニルアゾメチン及び2,2'-ジヒドロキシアゾベンゼン誘導体のガリウム及びアルミニウムキレートの物理化学的性質と蛍光強度との関係
  分析化学 BUNSEKI KAGAKU, 40, 495-498 (1991)
  Kimpei Yamamoto, Hisakazu Sunada, Yorinobu Yonezawa, Akinobu Otsuka:
  Relationship between the fluorescence intensities and physico-chemical properties of gallium and
  alminiumchelates of 2-hydroxyphenylazomethine and 2,2'-dihydroxyazobenzen derivatives

  分析化学,BUNSEKI KAGAKU, 40(9), 495-498 (1991)

                                        top
 長谷川浩司       46. 
46Masatoshi Ozawa, Koji Hasagawa, Yorinobu Yonazawa, Hisakazu Sunada:
  Preparation of Solid Dispersion for Ethenzamide-Carbopol and Theophyline-Carbopol System Using a Twin Screw Extruder  
  Chem. Pharm. Bull., 50( 6),   802  -  807 (2002)


                                        top
 服部亜紀 

                                        top
 服部直人              49 
49.木村 美保,島田 泰拓,大島 孝雄,柴田 大地,服部 直人,米澤 頼信,砂田 久一,
  粉末セルロースの医薬品賦形剤としての評価
  Miho Kimura, Yasuhiro Shimada, Takao Oshima, Daichi Shibata, Naoto Hattori, Yorinobu Yonezawa, Hisakazu Sunada:
  The Evaluation of Powdered Cellulose as a Pharmaceutical Excipient
  薬剤学,YAKUZAIGAKU, 62(3),113-123 (2002)


                                        top
 畢 雲霞             353739,54 
35Yunxia Bi,  Hisakazu Sunada,  Yorinobu Yonezawa,  Kazumi Danjo,  Akinobu Otsuka, Kotarou Iida,
  Preparation and Evaluation of a Compressed Tablet Rapidly Disintegrating in the Oral Cavity
  Chem. Pharm. Bull., 44 (11), 2121 -2127 (1996)
37Yunxia  Bi,  Hisakazu Sunada,  Yorinobu Yonezawa,  Kazumi Danjo,
  Evaluation of Rapidly Disintegrationg Tablets Prepared by a Direct Compression Method
  Drug Development and Industrial Pharmacy, 25(5), 571-581 (1999)
39Yunxia Bi,  Yorinobu Yonezawa,  Hisakazu Sunada;
  Rapidly Disintegrating Tablets Prepared by the Wet Compression Method : Mechanism and Optimization   
  J. Pharm. Sci., 88(10), 1004-1010 (1999)
54.大島 孝雄,畢 雲霞,米澤 頼信,砂田 久一:
  
難溶性薬物を含有する湿式法による口腔内速崩壊錠 - 調製と崩壊機構の解明

  Takao Oshima, Yunxia Bi, Yorinobu Yonezawa, and Hisakazu Sunada
  Wet-CompressedRapodly Disintegrating Tablets in the Oral Cavity Containing High-Content Poorly Water-Soluble Model Drug
  - Preparation and Cralification of Disintegration Mechanism

  薬剤学,YAKUZAIGAKU, 63(1), 1 -11 (2003)


                                        top
 古橋ひとみ              (acknowledgement in 13). 
13Hisakazu Sunada, Akio Yamamoto, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  Chem. Pharm. Bull., 36 (7), 2557 - 2561 (1988)

                                        top
 水野真里              41(36)  
41Yasuhiro Shimada,  Mayu Sunada,  Mari Mizuno,  Yorinobu Yonezawa,  Hisakazu Sunada,
  Kei Takebayashi,  Masahiko Yokosuka,  Haruki  Kimura:
  Measurement of the adhesive force of fine particles on tablet surface and method of their removal  
  Drug Development and Industrial Pharmacy, 26(2), 149-158 (2000)


                                        top
 宮永和美              (acknowledgement in 14). 
14Hisakazu Sunada, Yoshiko Hirai, Akinobu Otsuka, Yorinobu Yonezawa,
  Flocculation Studies of Granulated Stearyl Alcohol on the Surface of Aqueous Media.
  II. Flocculation-Deflocculation Mechanism in a Two-Dimensional System
   Chem. Pharm. Bull., 36 (9), 3584 - 3588 (1988)

                                        top
 山口秀夫             2530 
25山口秀夫,米澤頼信,檀上和美,砂田久一,瀬古則貴,石野隆三,
  センナ末の造粒における粉体物性と顆粒物性の関係
  Hideo Yamaguchi, Yorinobu Yonezaw, Kazumi Danjo, Hisakazu Sunada, Noritaka Seko, Ryuzo Ishino:
  Relationship between Characteristics of Powder and Granule on Granulation of Senna Powder
  薬剤学,YAKUZAIGAKU, 53(1), 70-79 (1993)
30山口秀夫,砂田久一,米澤頼信,檀上和美,
  生薬粉末の原料物性と製品物性との相関性
  Hideo Yamaguchi, Hisakazu Sunada, Yorinobu Yonezawa, Kazumi Danjo:
  Relationship between Characteristics of Raw Materials and Its Products of Crude Drug Powder
  薬剤学,YAKUZAIGAKU, 55(1), 17-27 (1995)


                                        top
 山崎敏正 

                                        top
 山路ひろこ     (acknowledgement in 22). 
22. 山本金平、砂田久一、米澤頼信、大塚昭信、
  2-ヒドロキシフェニルアゾメチン及び2,2'-ジヒドロキシアゾベンゼン誘導体のガリウム及びアルミニウムキレートの物理化学的性質と蛍光強度との関係
  分析化学 BUNSEKI KAGAKU, 40, 495-498 (1991)

  Kimpei Yamamoto, Hisakazu Sunada, Yorinobu Yonezawa, Akinobu Otsuka:
  Relationship between the fluorescence intensities and physico-chemical properties of gallium and
  alminiumchelates of 2-hydroxyphenylazomethine and 2,2'-dihydroxyazobenzen derivatives

  分析化学,BUNSEKI KAGAKU, 40(9), 495-498 (1991)

                                        top
 山田英理 


                                        top
 山田陽子     67
67.山田陽子,中村麻里子.島田泰拓,米澤頼信.砂田久一:
  乾式造粒法を用いた口腔内速崩壊錠の調製と評価 - 粉末セルロースの賦形剤としての利用 - 
  薬剤学,YAKUZAIGAKU, 66(6), 473 -481 (2006)
  Yoko Yamada, Mariko Nakamura, Yasuhiro Shimada, Yorinobu Yonezawa, Hisakazu Sunada:
  Preparation and Evaluation of Rapidly Disintegrating Tablet in the Oral Cavity by the Dry Compression Method
  - Availability of Powdered Cellulose as an Excipient -
  YAKUZAIGAKU, 66(6), 473 -481 (2006)


                                        top
 山田誉春              32
32Yoshihiro Aoki,  Yoshiharu Yamada,  Kazumi Danjo,  Yorinobu Yonezawa,  Hisakazu Sunada,
  Flocculation Kinetics of the Monodisperse System.
  II. Computer Simulation of Flocculation with Compaction by the Two-Dimensional Geometrical Random Coalescence Model     
  Chem. Pharm. Bull., 43 (7), 1197 -1203 (1995)


.
                                        top   MEMO
 山本昭夫              13. 
13Hisakazu Sunada, Akio Yamamoto, Akinobu Otsuka, Yorinobu Yonezawa,
  Changes of Surface Area in the Dissolution Process of Crystalline Substances
  Chem. Pharm. Bull., 36 (7), 2557 - 2561 (1988)


                                        top
 山本朱美 

                                        top
 山本智子 

                                        top
 若松しおり              (acknowledgement in 20)
20Yorinobu Yonezawa, Itaru Shinohara, Akinobu Otsuka, Hisakazu Sunada,
  Dissolution and Simulation Curves for Log-Normal Particle-Size-Distributed Model System
  Chem. Pharm. Bull., 38 (11), 3107 - 3111 (1990) 

.

                                        top   MEMO
 和田明子              33.  
33Yorinobu Yonezawa,  Shuichi Kawase,  Midori Sasaki,  Akiko Wada,  Hisakazu Sunada,
  Dissolution of Solid Dosage Form
  VI. Dissolution of Nondisintegrating Single Component Tablet under Non-Sink Condition
  Chem. Pharm. Bull., 43 (11), 1961 -1965 (1995)


.
                                        top   MEMO
 渡辺淳子                4. 
4.大塚昭信,米澤頼信,渡辺淳子
  ヨウ素法によるコール酸ナトリウムのミセル形成臨界濃度の測定
  Akinobu Otsuka, Yorinobu Yonezawa, Junko Watanabe:
  Determination of Critical Micelle Concentration of Sodium Cholate by Iodine Method
  薬学雑誌,YAKUGAKU ZASSHI, 99 (2), 217 - 219 (1979)



                                        top
 中村康彦                3 
3.Akinobu Otsuka, Yorinobu Yonezawa, Yasuhiko Nakamura,
  Physico-Chemical Properties of Glycyrrhizic Acid in Aqueous Media.
  II. Effect on Flocculation-Deflocculation Behavior of Suspensions of Sulfathiazole And Graphite     
  
J. Pharm. Sci., 67 (2), 151 - 154 (1978)

                                        top
 平井淑子             1418
14Hisakazu Sunada, Yoshiko Hirai, Akinobu Otsuka, Yorinobu Yonezawa,
  Flocculation Studies of Granulated Stearyl Alcohol on the Surface of Aqueous Media.
  II. Flocculation-Deflocculation Mechanism in a Two-Dimensional System
   Chem. Pharm. Bull., 36 (9), 3584 - 3588 (1988)
18Hisakazu Sunada, Yumiko Takahashi, Takashi Kurimoto, Yoshiko Hirai, Yorinobu Yonezawa,  
  Akinobu Otsuka, Yoshiaki Kawashima,
  Flocculation Studies of Granulated Stearyl Alcohol on the Surface of Aqueous Media.    
  III. Changes of Aggromerate Structure in a Two-Dimensional System with Anionic Surface- Active Agent   
  Chem. Pharm. Bull., 37 (12), 3355 - 3358 (1989)

.                                        top
 福居篤子              50,60 
50Atsuko Fukui, Ryuta Fujii, Yorinobu Yonazawa, Hisakazu Sunada:
  Analysis of Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules
  Chem. Pharm. Bull., 50(11), 1439 -11442 (2002)

61Atsuko Fukui, Ryuta Fujii, Yorinobu Yonezawa, Hisakazu Sunada:
  Analysis of Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules
  II. Effects of the Binder Solution on the Release Process
  Chem. Pharm. Bull., 52(3), 298 -302 (2004)
68.Atsuko Fukui, Ryuta Fujii, Yorinobu Yonezawa, Hisakazu Sunada:
  Analysis of Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules
  III.Effects of the Dissolution Condition on the Release Process
  Chem. Pharm. Bull., 54(8), 1091 -1096 (2006)
74.Atsuko Fukui, Ryuta Fujii, Yorinobu Yonezawa, Hisakazu Sunada
  
Analysis of the Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules lV.
   Evaluation of the Controlled Release Properties for in Vivo and in Vitro Release Systems    
 
  
Chem. Pharm. Bull., 55( 11), 1569 - 1573 (2007

76.Atsuko Fukui, Ryuta Fujii, Yorinobu Yonezawa, Hisakazu Sunada
  Analysis of the Release Process of Phenylpropanolamine Hydrochloride from Ethylcellulose Matrix Granules V .
  Release Properties of Ethylcellulose Layered Matrix Granules 
     Chem. Pharm. Bull., 56(4), 525 - 529 (2008)
 

                                        top
 辛 英 姫              ((co-work in 31))
31Haruo Sekizaki, Kazumi Danjo, Hiroshi Eguchi, Yorinobu Yonezawa, Hisakazu Sunada, Akinobu Otsuka,
  Solid-State Interaction of Ibuprofen with Polyvinylpyrrolidone
  Chem. Pharm. Bull., 43 (6), 988 - 993 (1995)

                                        top
 仲 偉 星              (acknowledgement in 36). 
36.田坂真粧美,砂田 久一,米澤 頼信,
  高濃度の主薬を含有するコーティング用核粒子の調製と評価
  Masami Tasaka, Hisakazu Sunada, Yorinobu Yonezawa:
  Characterization of Core Particles for Film Cating with High Active Ingredient Content
  薬剤学,YAKUZAIGAKU, 59(2), 57-66(1999)

                                        top
 李 暁蔓              24
24李 暁蔓,米澤頼信,檀上和美,砂田久一,松井 登,
  撹拌造粒によるセンナ末の二次構造
  Xiaoman Li, Yorinobu Yonezawa, Kazumi Danjo, Hisakazu Sunada, Noboru Matsui:
  Secondary Granulation of Senna Powder by Agitation Method
  薬剤学,YAKUZAIGAKU, 53(1), 63-69 (1993)


 王 暁燕                                         top
58王 暁燕,崔 福徳,米澤頼信,砂田久一:
  複合錠剤の調製と評価  - 配合禁忌を防止するための造粒とレイヤリングについて -
  Xiaoyan Wang, Fude Cui, Yorinobu Yonezawa, Hisakazu Sunada,
  Preparation and Evaluation of Combination Tablet Containing
  - Granulation and Layering to Prevent Incompatibility -
  薬剤学,YAKUZAIGAKU, 63(4), 207 -217 (2003)

59Xiaoyan Wang, Fude Cui, Yorinobu Yonezawa, Hisakazu Sunada,
  Preparation and Evaluation of High Drug Content Particles
  Drug Development and Industrial Pharmacy, 29(10), 1109-1118 (2003)



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