薬効解析学研究室 (ANALYTICAL PHARMACOLOGY)
教授 | 永松 正 (Professor Tadashi Nagamatsu, Ph. D. ) |
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准教授 | 小島良二 (Associate Professor Ryoji Kojima, Ph. D. ) |
助教 | 水野智博 (Assistant Professor Tomohiro Mizuno, Ph. D. ) |
① | 糖尿病性腎症の発症・進展機序の解明に向けた研究 |
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② | 新規分子シャペロン, Osp94および細胞周期関連分子の構造・機能に関する研究 |
③ | 腎不全患者における薬物療法の適正化に関する研究 |
Koji Hayashi, Yasumitsu Kano, Ryoji Kojima, Mikio Ito :Effects of a long-term administration of oral anti-diabetic agents on the progression of low dose streptozotocin-induced slowly progressive diabetes mellitus in mice
OyoYakuri/Pharmacometrics, 84, 19-27 (2013) |
Yasushi Hirasawa, Tsutomu Nishiyama, Toshiyuki Nagao, Yibin Feng, Tadashi Nagamatsu : Involvement of Protein Kinase C in Reduction of Aggregated Protein and Phosphorylation of CREB in Glomeruli
Exp. Anim. , 61, 119-124 (2012) |
Yasushi Hirasawa, Takayuki Sakai, Masanori Ito, Hiromitsu Yoshimura, Yibin Feng, Tadashi Nagamatsu : Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway
Eur. J. Pharmacol. , 672, 159-168 (2011) |
Yibin Feng, Ning Wang, Xingshen Ye, Huangyun Li, Yigang Feng, Fan Cheung, Tadashi Nagamatsu :Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats
J. Ethnopharmacol. , 138, 683-690 (2011) |
Akio Tanaka, Tadashi Nagamatsu, Makoto Yamaguchi, Atsushi Nomura, Fumiko Nagura, Kayaho Maeda, Tatsuhito Tomino, Tatsuhito Watanabe, Hideaki Shimizu, Yoshiro Fujita, Yasuhiko Ito :Myoclonus after dextromethorphan administration in peritoneal dialysis Ann. Pharmacother. , 45, 301 (2011) |
Masashi Ishihara, Ryoji Kojima, Mikio Ito : Influence of aging on gastric cytopretective and ulcer healing activities of sofalcone
Oyo Yakuri / Pharmacometrics, 80, 71-77 (2011) |
Ryoji Kojima. , Hajime Taniguchi, Aya. Tsuzuki, Kanoko Nakamura, Yumi Sakakura, Mikio Ito : Hypertonicityl-induced expression of monocyte chemoattractant protein-1 through a novel cis-acting element and MAP kinase signaling pathways
J. Immunol. , 184, 5253-5262 (2010) |
Kazuo Ishida, Ryoji Kojima, Makoto Tsuboi, Yuka Tsuda, Mikio Ito : Effect of Artichoke leaf extract on acute gastric mucosal injury in rats
Biol. Pharm. Bull. , 33, 223-229 (2010) |
Kazuo Ishida, Ryoji Kojima, Makoto Tsuboi, Yuka Tsuda, Mikio Ito : Anti-gastric action of Artichoke leaf extract mediated by endogenous prostaglangins
Oyo Yakuri / Pharmacometrics, 78, 59-66 (2010) |
Hiromitsu Yoshimura, Takayuki Sakai, Yusuke Kuwahara, Masayoshi Ito, Katsuki Tsuritani, Yasushi Hirasawa, Tadashi Nagamatsu : Effects of kynurenine metabolites on mesangial cell proliferation and gene expression
Exp. Mol. Pathol. , 87, 70-75 (2009) |
永松 正(分担執筆):催眠・鎮静薬, 抗不安薬, 抗精神病薬, 抗うつ薬 2011年度版 病院に行く前の覚える医薬品集-服薬指導に役立つ- pp. 1-12 廣川書店 (2011) |
永松 正(分担執筆):第7章 腎臓・泌尿器に作用する薬物 第3版 最新基礎薬理学 pp. 225-240 廣川書店 (2011) |
永松 正(分担執筆):ネフローゼ症候群 リアリスティック続薬学複合問題 pp. 60-71 廣川書店 (2011) |