薬品作用学研究室 (CHEMICAL PHARMACOLOGY)
| 教授 | 平松 正行（Professor Masayuki Hiramatsu, Ph.D.） |
|---|---|
| 准教授 | 間宮 隆吉（Associate Professor Takayoshi Mamiya, Ph.D.） |
| 助教 | 衣斐 大祐（Assistant Professor Daisuke Ibi, Ph.D.） |
| ① | 学習・記憶の機序および認知症病態の解析と予防法、治療薬の開発に関する研究 |
|---|---|
| ② | ストレスと神経精神疾患に関する研究 |
| ③ | ストレス関連疾患モデルの作製と予防・治療法の開発 |
| ④ | 薬物依存に関する研究 |
| Joseph A, Tang M, Mamiya T, Chen Q, Yang L, Jiao J, Yu N, Tang YP.： A temporal association of elevated CCKergic tone and adolescent trauma is critical for PTSD-like behavior in adult mice. Proc Natl Acad Sci USA, 110: 6589-6594 (2013) |
| Ikeda Y, Mamiya T, Nishiyama H, Koseki T, Mouri A, Nabeshima T.： Predictive factors for infection by extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli in hospitalized patients. Nagoya J Med Sci, 74: 93-104 (2012) |
| Miwa M, Tsuboi M, Noguchi Y, Enokishima A, Nabeshima T, Hiramatsu M.： Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2. J Neuroinflammation, 8: 153 (2011) |
| Alkam T, Hiramatsu M, Mamiya T, Aoyama Y, Nitta A, Yamada K, Kim HC, Nabeshima T.： Evaluation of object-based attention in mice. Behav Brain Res, 220: 185-193 (2011) |
| Hiramatsu M, Takiguchi O, Nishiyama A, Mori H.： Cilostazol prevents amyloid beta peptide (25-35)-induced memory impairment and oxidative stress in mice. Br J Pharmacol, 161: 1899-1912 (2010) |
| Miwa M, Uchida S, Horiba F, Takeshima H, Nabeshima T, Hiramatsu M.： Nociceptin and its metabolite attenuate U0126-induced memory impairment through a nociceptin opioid peptide (NOP) receptor-independent mechanism. Neurobiol Learn Mem, 93: 396-405 (2010) |
| Tomida S, Mamiya T, Sakamaki H, Miura M, Aosaki T, Masuda M, Niwa M, Kameyama T, Kobayashi J, Iwaki Y, Imai S, Ishikawa A, Abe K, Yoshimura T, Nabeshima T, Ebihara S.： Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests. Nature Genetics, 41: 688-695 (2009) |
| Lu P, Mamiya T, Lu LL, Mouri A, Zou L, Nagai T, Hiramatsu M, Ikejima T, Nabeshima T.： Silibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice. Br J Pharmacol, 157: 1270-7 (2009) |
| Miwa M, Shinki C, Uchida S, Hiramatsu M.： Distinct effects of nociceptin analogs on scopolamine-induced memory impairment in mice. Eur J Pharmacol, 602: 328-33 (2009) |
| Hiramatsu M, Miwa M, Hashimoto K, Kawai S, Nomura N.： Nociceptin/orphanin FQ reverses mecamylamine-induced learning and memory impairment as well as decrease in hippocampal acetylcholine release in the rat. Brain Res, 1195: 96-103 (2008) |
| ロバート・フリードマン (著)、鍋島 俊隆 (翻訳・監修) (分担翻訳：平松 正行、間宮 隆吉)： 我々の内なる狂気 統合失調症は神経生物学的過程である 星和書店、東京（2011） |
| 平松正行：GraphPad Prism 5による医学・薬学・生物系のための生物統計学入門
カットシステム(2010) |